KEM Karl Fisher Moisture Titrators
Karl Fischer Moisture Titrator measures micro amounts of water content which exists in liquid or in solid sample material. Operated easily and generating results quickly with high precision and accuracy. The Karl Fischer Moisture Titrator from KEM has supported this analysis since the 1960s.

Hybrid Karl Fischer Moisture Titrator
MKH-710M
- Hybrid titration method
- Easy factor determination by “Electrolytic Factor Measurement System”
- Unique integrated “Hybrid titration cell” of both “Volumetric titration method” & “Coulometric titration method”
Automatic sample injection
Hybrid titration method automatically switches the measurement methods of volumetric and coulometric according to the water content of the sample.
You can accurately and seamlessly measure samples without concern for the sample moisture content, as the instrument is capable of measuring trace or much larger quantities.
No need to inject pure water Fully automatic factor measurement
Our unique “Electrolytic Factor Measurement System” carries out factor measurement automatically.
Just the press of a button enables factor measurement, which alleviates the need for
the tedious weighing or measuring of pure water.
Single instrument and a single titration cell allow utilization of Volumetric/Coulometric/Hybrid Titration Methods.
Just one instrument with one titration cell is needed to perform volumetric, coulometric, and hybrid easurements.
With high operability for the volumetric method, the requisite sealability for the coulometric method has also been realized.
Integrated functionality greatly contributes to a ompact installation and low maintenance requirements.
- Titrant Information is stored in an IC chip in the burette unit (Smart burette)
- New burette unit
- Up to 4 simultaneous measurements (Simultaneous titrations)
- Can be connected to AT-710B potentiometric titrators ,MKV-710B volumetric Karl Fischer moisture titrators MKC-710B Coulometric Karl Fischer moisture titrators
- The main control unit and a titrator are separately located by wireless (Bluetooth(R))
- Large color TFT-LCD with a touch panel (8.4-inch)
- Two different user levels and permissions
- Measurement results are converted to PDF and can be stored in a USB flash drive
- Navigation function of Karl Fischer reagent replacement
- Automatic solvent change unit is included
Karl Fischer Moisture Titrator (Volumetric titration) MKV-710M
- Large color TFT-LCD with a touch panel (8.4-inch) enables easy key entry
- Up to 4 titrators, AT-710B potentiometric titrators, MKC-710B Coulometric or MKH-710/2nd Hybrid or additional MKV-710B Volumetric Karl Fischer moisture titrators can be connected and simultaneous measurement is possible
- Can resume titration automatically after interruption
- The MKV-710M contains functions to support compliance with the following:
- European Pharmacopoeia Chapter 2.5.12. WATER: SEMI-MICRO DETERMINATION: SUITABILITY
- Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method): 1.4 Suitability of determination
- Titrant Information is stored in an IC chip in the burette unit (Smart burette)
- New burette unit
- Up to 4 simultaneous measurements (Simultaneous titrations)
- Can be connected to AT-710B potentiometric titrators, MKC-710B Coulometric Karl Fischer moisture titrators or MKH-710/2nd Hybrid Karl Fischer moisture titrators
- The main control unit and a titrator are separately located by wireless (Bluetooth(R))
- Large color TFT-LCD with a touch panel (8.4-inch)
- Two different user levels and permissions
- Measurement results are converted to PDF and can be stored in a USB flash drive
- When using ADP-611 , a patented scan mode automatically determines the optimal evaporation temperature.
- End point detection by compensating liquid resistance is adopted.
- Can resume titration automatically after interruption
- Automatic solvent change unit is included
Karl Fischer Moisture Titrator (Volumetric titration) MKV-710S
- Large color TFT-LCD with a touch panel (8.4-inch) enables easy key entry
- Can resume titration automatically after interruption
- The MKV-710S contains functions to support compliance with the following:
- European Pharmacopoeia Chapter 2.5.12. WATER: SEMI-MICRO DETERMINATION: SUITABILITY
- Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method): 1.4 Suitability of determination
- Titrant Information is stored in an IC chip in the burette unit (Smart burette)
- New burette unit
- Large color TFT-LCD with a touch panel (8.4-inch)
- Two different user levels and permissions
- Measurement results are converted to PDF and can be stored in a USB flash drive
- When using ADP-611 , a patented scan mode automatically determines the optimal evaporation temperature.
- End point detection by compensating liquid resistance is adopted.
- Can resume titration automatically after interruption
- Automatic solvent change unit is included

Karl Fischer Moisture Titrator (Volumetric titration) MKV-710D
MKV-710D is a Karl Fischer moisture titrator (Volumetric titration) developed to support DI (Data Integrity) based on GMP (Good Manufacturing Practice).
Access Restrictions
Operators are authenticated to log on by an operator ID and password.
Only one operator can log on the system and operators can be changed via the logon/logoff function. Up to 100 operators can be registered, and an ID and password are registered for each operator.
Only one operator can log on even when 2 channels are connected.
An operator cannot log off during measurement.
Rights Administration
You can assign the authorities to edit and set the functions to each operator.
There are five preset rights groups, and you can also create up to 10 rights groups arbitrarily according to the usage at your site.
Reliability improved by assigning each operator to a rights group.
Electronic Approval / Electronic Signature
The electronic approval workflow consists of five stages: Check, Confirmation, and Approval, are in sequence, as well as denial, and unchecked status.
The signature level cannot be skipped, and always has to be signed in the Check, Confirmation, and Approval sequence.
A password is required when signing.
The signature details can be checked in the signature log.
Dl support function
- Access Restrictions : Operator authentication by operator ID and password
- Rights Administration : Each operator is assigned to a specific right group
- Audit Trail : Operation histories are automatically recorded
- Electronic Approval / Electronic Signature : Electronic approval and signature based on the workflow
- Backup / Restoration : Automatic backup with the predetermined period
- Archive / Archive View : Data storage. Archive data can be viewed on the main control unit
- Data Capacity : The remaining capacity can be checked any time via an icon on the main screen
- Security Settings : Password length and lockout settings can be set
- LIMS Connection : Data output to LIMS systems
- The MKV-710M contains functions to support compliance with the following:
- European Pharmacopoeia Chapter 2.5.12. WATER: SEMI-MICRO DETERMINATION: SUITABILITY
- Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method): 1.4 Suitability of determination
- Large color TFT-LCD with a touch panel (8.4-inch)
- The main control unit and a titrator are separately located by wireless (Bluetooth(R)).
- Measurement results can be saved in PDF files.
- The Water content can be displayed in real time.
- Burettes can be selected from 1-unit and 2-unit types
- Not necessary to change the electrode sensitivity and endpoint potential
Karl Fischer Moisture Titrator (Volumetric titration) MKV-710B
High-performance titrator at a lower price.
New burette unit
The new burette unit has the switching valve mounted directly on top of the cylinder. Less dead space between the switching valve and the cylinder and it inside of the cylinder left less residual titrant when replacing it.
No need to adjust settings for different types of solvent and samples
KEM's proprietary technology (endpoint detection by compensating liquid resistance) makes it unnecessary to change the detection electrode sensitivity and the endpoint voltage depending on the nature of each solvent and sample. This feature reliably prevents over titration and ensures highly accurate measurements.
Easy injection/drain of dehydrated solvent
The stirrer unit is equipped with a pump for injecting/draining dehydrated solvent. Once you set the operating time of the pump with the internal timer, the optimum quantity of the solvent is automatically injected.
- Measurement results are converted to PDF and can be stored in a USB flash drive
- End point detection by compensating liquid resistance is adopted.
- Can resume titration automatically after interruption
- By connecting an Android device , a titration curve can be displayed in real-time
Karl Fischer Moisture Titrator (Coulometric titration) MKC-710M
- Large color TFT-LCD with a touch panel (8.4-inch) enables easy key entry
- Up to 4 titrators, AT-710B potentiometric titrators, MKV-710B Volumetric or MKH-710/2nd Hybrid or additional MKC-710B Coulometric Karl Fischer moisture titrators can be connected and simultaneous measurement is possible
- Reduction of power consumption by 30% compared with the conventional product
- The MKC-710M contains functions to support compliance with the following:
- European Pharmacopoeia Chapter 2.5.32. WATER: MICRO DETERMINATION: VERIFICATION OF ACCURACY
- Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method): 2.4 Suitability of determination
- Up to 4 simultaneous measurements (Simultaneous titrations)
- Can be connected to AT-710B potentiometric titrators, MKV-710B Volumetric Karl Fischer moisture titrators or MKH-710/2nd Hybrid Karl Fischer moisture titrators
- The main control unit and a titrator are separately located by wireless (Bluetooth(R))
- Large color TFT-LCD with a touch panel (8.4-inch)
- Two different user levels and permissions
- With a unique mechanism , the ceramic diaphragm of the optional titration cell unit can be replaced
- Measurement results are converted to PDF and can be stored in a USB flash drive
- By reviewing the conventional electrolytic control method , reduction of power consumption by 30%
- When using ADP-611 , a patented scan mode automatically determines the optimal evaporation temperature.
- Manual solvent change unit is included
Karl Karl Fischer Moisture Titrator (Coulometric titration) MKC-710S
- Large Large color TFT-LCD with a touch panel (8.4-inch) enables easy key entr
- Reduction of power consumption by 30% compared with the conventional product
Fast measurements
KEM's proprietary technology achieves electrolytic speeds up to 2.6mg H2O/min. This shortens the time required for pre-titrations and sample measurements considerably.
- The MKC-710S contains functions to support compliance with the following:
- European Pharmacopoeia Chapter 2.5.32. WATER: MICRO DETERMINATION: VERIFICATION OF ACCURACY
- Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method): 2.4 Suitability of determination
- Large color TFT-LCD with a touch panel (8.4-inch)
- Two different user levels and permissions
- With a unique mechanism , the ceramic diaphragm of the optional titration cell unit can be replaced
- Measurement results are converted to PDF and can be stored in a USB flash drive
- By reviewing the conventional electrolytic control method , reduction of power consumption by 30%
- When using ADP-611 , a patented scan mode automatically determines the optimal evaporation temperature.
- Manual solvent change unit is included
Karl Fischer Moisture Titrator (Coulometric titration) MKC-710D
MKC-710D is a Karl Fischer moisture titrator (Coulometric titration) developed to support DI (Data Integrity) based on GMP (Good Manufacturing Practice).
Access Restrictions
Operators are authenticated to log on by an operator ID and password.
Only one operator can log on the system and operators can be changed via the logon/logoff function. Up to 100 operators can be registered, and an ID and password are registered for each operator.
Only one operator can log on even when 2 channels are connected.
An operator cannot log off during measurement.
Rights Administration
You can assign the authorities to edit and set the functions to each operator.
There are five preset rights groups, and you can also create up to 10 rights groups arbitrarily according to the usage at your site.
Reliability improved by assigning each operator to a rights group.
Electronic Approval / Electronic Signature
The electronic approval workflow consists of five stages: Check, Confirmation, and Approval, are in sequence, as well as denial, and unchecked status.
The signature level cannot be skipped, and always has to be signed in the Check, Confirmation, and Approval sequence.
A password is required when signing.
The signature details can be checked in the signature log.
Data integrity support functions without a PC
Dl support function
- Access Restrictions : Operator authentication by operator ID and password
- Rights Administration : Each operator is assigned to a specific right group
- Audit Trail : Operation histories are automatically recorded
- Electronic Approval / Electronic Signature : Electronic approval and signature based on the workflow
- Backup / Restoration : Automatic backup with the predetermined period
- Archive / Archive View : Data storage. Archive data can be viewed on the main control unit
- Data Capacity : The remaining capacity can be checked any time via an icon on the main screen
- Security Settings : Password length and lockout settings can be set
- LIMS Connection : Data output to LIMS systems
- The MKC-710D contains functions to support compliance with the following:
- European Pharmacopoeia Chapter 2.5.32. WATER: MICRO DETERMINATION: VERIFICATION OF ACCURACY
- Japanese Pharmacopoeia Eighteenth Edition Chapter 2.48: Water determination (Karl Fischer Method): 2.4 Suitability of determination
- Large color TFT-LCD with a touch panel (8.4-inch)
- The main control unit and a titrator are separately located by wireless (Bluetooth(R)).
- Measurement results can be saved in PDF files.
- The Water content can be displayed in real time.
- Energy saving designed.
- Maximum 2.6mgH2O/min of electrolysis speed.
Karl Fischer Moisture Titrator (Coulometric titration) MKC-710B
- High-performance titrator at a lower price
- Reduction of power consumption by 30% compared with the conventional product
Fast measurements
KEM's proprietary technology achieves electrolytic speeds up to 2.6mg H2O/min.
This shortens the time required for pre-titrations and sample measurements considerably.
Replaceable diaphragm
Easy maintenance when measuring samples which tend to contaminate the diaphragm as eg. oils: Thanks to a unique mechanism, the ceramic diaphragm of the optional titration cell unit (12-03635-01) can be replaced.
Result output as PDF files
Paper saving and environmentally friendly – results no longer need to be printed.
Measurement results are converted to PDF and can be stored in a USB flash drive.
- By reviewing the conventional electrolytic control method , reduction of power consumption by 30%
- Field measurements without access to power sources are possible by connecting a commercially available battery
- By connecting an Android device , a titration curve can be displayed in real-time
- Measurement results are converted to PDF and can be stored in a USB flash drive

KEM Aqua Karl Fischer Reagents “KEMAQUA Series"
Karl Fischer Reagent “KEMAQUA Series" is a reagent made by Kyoto Electronics Manufacturing for use with Karl Fischer Moisture titrator.
It is available for a wide range of samples.

Data Acquisition Software
Software for Moisture Titrator